Protesters targeted Newsprinters presses at Broxbourne in Hertfordshire, Knowsley in Merseyside, and near Motherwell, North Lanarkshire.
Prime Minister Boris Johnson said the action by demonstrators across the country was “unacceptable”.
Eighty people have been arrested.
The presses print the Rupert Murdoch-owned News Corp titles including the Sun, the Times, the Sun on Sunday, the Sunday Times, and the Scottish Sun. They also print the Daily Telegraph and Sunday Telegraph, the Daily Mail and Mail on Sunday, and the London Evening Standard.
Demonstrators have accused the papers of failing to report on climate change.
XR used vehicles to block roads to the printing plants, while individual protesters chained themselves to structures.
Vans were covered with banners with messages including “Free the truth” and “Refugees are welcome here”.